Introduction. The complete blood count is an important diagnostic tool, with laboratory protocols and reference ranges well established in both human medicine. The hematocrit values of fish blood range from almost 0 to more than 50% in actively swimming, surface-feeding species. Mature fish red cells usually are oval and disk-shaped with a compact nucleus. Read 9 answers by scientists with 4 recommendations from their colleagues to the question asked by Rinku Arora on May 31,


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The variations in shape may be due to cell maturation or degree of activation.

Fish red blood cells: characteristics and physiological role of the membrane ion transporters.

Thrombocytes are often confused with the fish blood cells lymphocyte; this similarity contributes to error in the total white cell count and on the differential. On the blood smear, the key features that distinguish the thrombocytes from lymphocytes are the cytoplasm color colorless vs.

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C ratio higher in the lymphocyte. Fish fish blood cells are an important part of the clotting process: Multiple authors have described a second population of thrombocytes in some elasmobranch species that is identical to the fish blood cells thrombocyte with the exception that the cytoplasm is filled with slender rod-shaped eosinophilic granules.


Fish blood cells to those found in birds and reptiles, fish lymphocytes are small round cells with a high N: C ratio and a rim of smooth light blue cytoplasm around the large oval-round condensed nucleus. Some authors further classify the size as small and large, although the functional difference is not yet understood.

Hematology and Blood Chemistry for Fish Species | The Fish Site

As with lymphocytes, the morphology of fish monocytes is comparable to those found in mammals, birds, and reptiles. The monocytes are large, usually round cells with abundant blue cytoplasm often fish blood cells vacuoles. The nucleus can be round, oval, or lobed with loosely compact chromatin.

The morphology of fish basophils is similar fish blood cells that of terrestrial animals.

They are extremely rare in most teleosts but are commonly found in low numbers on peripheral blood smears from stingray species Arnold, unpublished data.

The nucleus is usually difficult to observe fish blood cells to the abundance of granules. Teleost neutrophils are large round cells with abundant clear cytoplasm and an eccentric, condensed nucleus that is either round or multi-lobed. The cytoplasm is often light gray and, in some cells, contains very fine fish blood cells granules.

This cell type is sometimes reported as heterophil in the literature, but to those familiar with avian and fish blood cells blood the term heterophil indicates a different cell type one with rod-shaped red cytoplasmic granules.

The functional distinction for these two cell morphology types in fish is not yet well understood Neutrophils in elasmobranchs appear as large cells with clear colorless cytoplasm containing fish blood cells round or multi-lobed condensed nucleus, often both found on the same blood smear.

Mainwaring and Rowley termed this cell as the G2 of the G series. The literature varies in fish blood cells nomenclature used to describe the variety of fish cells containing eosinophilic granules.

Teleost cells often fish blood cells described using the classification for birds and reptiles, where elasmobranch cells are described in a variety of nomenclature systems. Large round cell with clear to pale blue-gray cytoplasm filled with slender rod-shaped eosinophilic granules. The nucleus can be either round or multi-lobed.

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Before mammals, nucleated blood cells were the norm. Mammals evolved enucleated blood cells to use oxygen more efficiently. Two, birds have a different respiratory system that lets them transport oxygen efficiently without needing enucleated blood cells. They have fish blood cells respiration that lets air move continuously through the body.