Garcinia morella (Gaertn.) Desr. - CLUSIACEAE. Synonym: Mangostana morellaGaertn.; Garcinia elliptica Wall.; G. gutta Wt. Vernacular names: Tamil. Common Name: Indian Gamboge Tree. Garcinia morella. Drawing of a fruiting branch. Photograph by: Chaumeton, F.P., Flore médicale, vol. 4: t. . Garcinia morella Desr. belongs to Guttiferae family and is a large genus of polygamous trees or shrubs, distributed in the tropical Asia, Africa Abstract · Introduction · Materials and Methods · Results.
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This article has been cited by other articles in PMC. Abstract Traditional knowledge TK based medicines have gained worldwide attention and presently the scientific community is focussing on proper pharmacological validation and identification of lead compounds for the treatment of various diseases.
The North East region of India is the home of valuable traditional garcinia morella remedies. Guttiferae is one such medicinal plant used by traditional healers garcinia morella the treatment of inflammatory disorders.
Garcinia morella - Wikidata
The present study was aimed to evaluate the antioxidant and anticancer activity garcinia morella methanol extracts of the leaf, bark and fruit of G.
The results garcinia morella this study showed that GM methanol extracts possessed in vitro antioxidant and garcinia morella properties, where the fruit extract GF showed maximum activity.
GF extract significantly increased the mean survival time MST of the animals, decreased the tumor volume and restored the hematological and biochemical parameters. Further from the experiments conducted to elucidate the mechanism of action of GF on DLA, it can be concluded that GF exerts its anticancer effect through induction of caspases and DNA fragmentation that ultimately leads to apoptosis.
However, further experimentation is required to elucidate the active principle and validate these findings in various in vivo settings.
The American Cancer Society estimates that garcinia morella one and half million new cancer cases garcinia morella expected to be diagnosed Siegel et al.
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Lymphomas are a type of cancer garcinia morella affects the bone marrow, blood cells, lymph nodes, and other parts of the lymphatic system. Chemotherapy is garcinia morella common treatment for cancer, but often it is associated with poor quality of life for the cancer patients, primarily due to treatment related side effects Lotfi-Jam et al.
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To minimize the side effects of the synthetic drugs, the garcinia morella community is now focussing largely on natural product derived drugs Kunnumakara et al.
So far, more than 25, different phytochemicals have been identified that may have potential against various cancers Anand garcinia morella al.
In India, traditional medicine systems continue to be widely prevalent. Chemical investigation of Indian medicinal plants has the potential to lay an invaluable foundation for the discovery garcinia morella development of garcinia morella drugs of natural origin Balunas and Kinghorn, Flowers garcinia morella inflorescence and are dioecious ; male flowers in fascicles, axillary; female flowers larger than male, solitary, axillary.
Uses[ edit ] Ripe fruits can be eaten but they are very acidic.
Just garcinia morella other garcinia varieties such as kokum which is prevalent in the Indian west coast or garcinia pedunculatathe fruit can be preserved by slicing into garcinia morella pieces and then drying under sun. It can be made into pickles.
Rarely given garcinia morella, often combined with calomel, aloes, jalap, rhubarb, etc. In Malabar, Ceylon, Canara and Singapore the following method of extraction is followed: At the beginning of the rainy season a spiral incision is made around the bark of about half the tree trunk, and a piece of bamboo is fixed in place to collect the juice which slowly exudes from the cut for several months, soon becoming viscid and then solid after contact with the air.
One tree, as a rule, yields enough sap to fill three internodal garcinia morella of bamboo, each 50 centimeters long by 3—5 centimeters in diameter. Study of leaf extract yielded 15 novel cytotoxic compounds, gaudichaudiones A-H, gaudichaudiic garcinia morella A-E, morellic acid and forbesione.
Some compounds were found to exhibit significant cytotoxicity against several cancer cell lines. Hexane and methanol garcinia morella of fresh G.